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Welcome to chanda.labs positions available Post-Doctoral Associate. Available for individuals with expertise in molecular virology or innate immune signaling. Research focus will involve elucidation of host cellular factors required for viral (influenza, Dengue, West Nile, & HIV) infection, and identification of novel proteins involved in Pattern Recognition Receptor (PRR) signaling. Approaches will exploit large-scale function genomics technologies, including global RNAi analysis, as tools understand the mechanistic implications of these host-pathogen interactions. Systems & Wet-bench Research. Projects include using systems-based approaches to: (i) understand early innate responses to HIV infection (see also http://www.hint.org/) (ii) dissect innate signaling pathways that response to nucleic acid PAMPs (iii) elucidate cellular restriction mechanisms of flaviviral replication (iv) discover host-pathogen interactions that regulate viral replication (v) develop novel anti-viral therapies Computational Biology. We are seeking to recruit a skilled computational biologist with experience developing analysis and database integration solutions for orthogonal systems-level datasets, including high throughput genomics, proteomics, and microarray/NGS. Knowledge of bioinformatics is required, particularly hands on experience in the area of statistics, protein network analysis, pathway enrichment analysis, gene expression clustering are important. The candidate will develop novel methods, extend, adapt and improve existing methods. Requirements Qualifications: This position requires the knowledge and skills normally acquired through completion of a PhD in bioinformatics, statistics, computer science, computational biology, or engineering (MS acceptable for the candidate with the right experience). Programming skills in R/Perl on a UNIX platform and knowledge of machine learning approaches is preferred. Rapid prototyping experience is essential. Interested, qualified applicants should email their Curriculum Vitae including names and correspondence of three references to Crystal Herndon, cherndon@burnham.org.. |
