Publications

2019

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.

Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK.

Nat Commun. 2019 Apr 3;10(1):1523. doi: 10.1038/s41467-019-09234-6.

PMID: 30944313 Free PMC article.

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.

Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus PD, Herbert KM, Pache L, Smith N, van der Merwe JA, Chanda SK, Fellay J, Kirchhoff F, Sauter D.

Elife. 2019 Feb 5;8:e41930. doi: 10.7554/eLife.41930.

PMID: 30717826 Free PMC article.

SNW1, a Novel Transcriptional Regulator of the NF-κB Pathway.

Verma S, De Jesus P, Chanda SK, Verma IM.

Mol Cell Biol. 2019 Jan 16;39(3):e00415-18. doi: 10.1128/MCB.00415-18. Print 2019 Feb 1.

PMID: 30397075 Free PMC article.

HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking.

Marin M, Kushnareva Y, Mason CS, Chanda SK, Melikyan GB.

Viruses. 2019 Jan 25;11(2):100. doi: 10.3390/v11020100.

PMID: 30691001 Free PMC article.

2018

Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.

Jain P, Boso G, Langer S, Soonthornvacharin S, De Jesus PD, Nguyen Q, Olivieri KC, Portillo AJ, Yoh SM, Pache L, Chanda SK.

Cell Rep. 2018 Feb 27;22(9):2493-2503. doi: 10.1016/j.celrep.2018.01.091.

PMID: 29490283 Free PMC article.

Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.

White KM, Abreu P Jr, Wang H, De Jesus PD, Manicassamy B, García-Sastre A, Chanda SK, DeVita RJ, Shaw ML.

ACS Infect Dis. 2018 Feb 9;4(2):146-157. doi: 10.1021/acsinfecdis.7b00120. Epub 2018 Jan 4.

PMID: 29268608 Free PMC article.

2017

Identification of Polo-like kinases as potential novel drug targets for influenza A virus.

Pohl MO, von Recum-Knepper J, Rodriguez-Frandsen A, Lanz C, Yángüez E, Soonthornvacharin S, Wolff T, Chanda SK, Stertz S.

Sci Rep. 2017 Aug 17;7(1):8629. doi: 10.1038/s41598-017-08942-7.

PMID: 28819179 Free PMC article.

Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.

Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VR, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK.

Nat Microbiol. 2017 Mar 1;2:17022. doi: 10.1038/nmicrobiol.2017.22.

PMID: 28248290 Free PMC article.

2016

A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.

Gong D, Kim YH, Xiao Y, Du Y, Xie Y, Lee KK, Feng J, Farhat N, Zhao D, Shu S, Dai X, Chanda SK, Rana TM, Krogan NJ, Sun R, Wu TT.

Cell Host Microbe. 2016 Nov 9;20(5):642-653. doi: 10.1016/j.chom.2016.10.004.

PMID: 27832591 Free PMC article.

NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.

Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP.

Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001.

PMID: 27078069 Free PMC article.

The Chanda Lab