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Open Positions: Senior Research Scientist (Drug Discovery)

The Chanda Lab @ Calibr in La Jolla, CA, has an open position for a Senior Research Scientist to lead a team of researchers - including RAs, graduate students, and postdoctoral fellows - focused on drug discovery/development for viruses with pandemic potential. Several projects are embedded in AVIDD ( while others are funded by the DoD and the Gates Foundation. The Senior Research Scientist will play an important intellectual, technical, and scientific role in leading and expanding projects in this area and will interface with external collaborators while mentoring direct reports. They will also lead grant-writing and manuscript-writing efforts. This is a fully supported, non-tenure track position.


                                        Essential Duties and Responibilities

  • Initiate and execute laboratory research in a timely manner, and develop strategies to discover innovative antivirals

  • Initiate and execute laboratory research in a timely manner, and develop strategies to discover innovative antivirals

  • Investigate the feasibility of applying a wide variety of scientific principles and concepts to potential inventions

  • Maintain broad knowledge of virology and large-scale technologies (proteomics/chemoproteomics, chemical biology, NextGen Sequencing, etc.)

  • Adhere to the safety regulations to handle BSL2- and BSL3-level viruses, human primary cells, and cell lines

  • Accurate data analysis using Excel, Prism and other tools, and lab notebook documentation

  • Preparation of reports and presentation of research results at regular team meetings

  • Write scientific manuscripts and grant applications

  • Present research results at conferences

  • Mentor junior scientists to troubleshoot their experiments

                                       Qualifications and Experience

  • Initiate and execute laboratory research in a timely manner, and develop strategies to discover innovative antivirals

  • Ph.D. degree in biological science, biochemistry, microbiology, or related field

  • Minimum 6+ years post-doctoral experience

  • Strong background in virology

  • Background in innate immunity is a plus

  • Knowledge of assay development and drug discovery is required

  • Significant expertise in cell/tissue culture, including the isolation and manipulation of primary cells

  • Functional genomics and bioinformatic experience is a plus

  • Knowledge or experience in the fields of drug discovery and in vivo studies is a plus

  • Experience in working with viruses: stock generation, determining infectious titers, setting up in vitro antiviral assays are required

  • Experience with cell-based and biochemical assays using methods such as high-content imaging, luminescence, fluorescence and absorbance are preferred

  • Excellent oral and written communications skills

  • Demonstrated productivity with a strong publication record in high-quality journals

  • Ability to work in a highly dynamic environment with excellent organizational skills and the ability to work independently

Physical Demands and Work Environment:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions. Details of established essential functions for this position will be addressed/discussed during the interview process.

Please submit a CV/Biosketch and a Cover Letter to or the Scripps portal, addressing the following topics:

(i) how does your research experience fit with our science?

(ii) what can you uniquely bring toour research program & lab?

(iii) what are your long-term professional goals, and how can joining our team fit in these goals?

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